Megamind (Will Ferrell), a super-intelligent alien, has constantly battled his nemesis Metro Man (Brad Pitt) since they both arrived on Earth as infants. Consistently losing to Metro Man, Megamind believes himself destined to be the villain. On the day that Metro City dedicates a museum to their protector, Megamind and his sidekick Minion (David Cross) kidnap reporter Roxanne (Tina Fey), and then lure Metro Man into a copper-lined room. To everyone's surprise, Metro Man is unable to escape, and appears to be killed when Megamind's death ray strikes him. Megamind revels in his victory, but shortly becomes depressed, his villainy having no meaning without anyone to stop him.
